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Effects of univalent cations on the properties of...
Journal article

Effects of univalent cations on the properties of yeast NAD+ acetaldehyde dehydrogenase

Abstract

Acetaldehyde dehydrogenase (aldehyde:NAD(P)+ oxidoreductase, EC 1.2.1.5) from yeast is activated by K+ and Rb+. Sodium and Li+ antagonize the activation, apparently by competitive inhibition with K+. The stimulation of activity by mercaptoethanol and the activation by K+ are not additive in a reaction mixture containing both. Potassium and Rb+ in the order just mentioned protect acetaldehyde dehydrogenase from inactivation by heat, whereas Na+ …

Authors

Sorger GJ; Evans HJ

Journal

Biochimica et Biophysica Acta, Vol. 118, No. 1, pp. 1–8

Publisher

Elsevier

Publication Date

January 1966

DOI

10.1016/s0926-6593(66)80139-x

ISSN

0006-3002