Journal article
Prophylactic acid suppressants in patients with primary neurologic injury: A systematic review and meta-analysis of randomized controlled trials
Abstract
PURPOSE: Neurocritical care patients are at risk of stress-induced gastrointestinal ulceration. We performed a systematic review and meta-analysis of stress ulcer prophylaxis (SUP) in critically ill adults admitted with a primary neurologic injury.
MATERIALS AND METHODS: We included randomized controlled trials (RCTs) comparing SUP with histamine-2-receptor antagonists (H2RAs) or proton pump inhibitors (PPIs) to placebo/no prophylaxis, as well …
Authors
Daou M; Dionne JC; Teng JFT; Taran S; Zytaruk N; Cook D; Wilcox ME
Journal
Journal of Critical Care, Vol. 71, ,
Publisher
Elsevier
Publication Date
October 2022
DOI
10.1016/j.jcrc.2022.154093
ISSN
0883-9441