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PTH 1-34-functionalized bioactive glass improves...
Journal article

PTH 1-34-functionalized bioactive glass improves peri-implant bone repair in orchiectomized rats: Microscale and ultrastructural evaluation

Abstract

The objective of this work was to investigate the use of Biogran® functionalized with parathyroid hormone (PTH) 1-34 by sonochemistry for the local delivery of this anabolic agent to the implant site. The effects of Biogran® and topical administration of PTH 1-34 on peri-implant bone regeneration were evaluated from the microscale to ultrastructural levels in healthy (SHAM) and orchiectomized (ORQ). While some animals only received a titanium …

Authors

Gomes-Ferreira PHS; Micheletti C; Frigério PB; de Souza Batista FR; Monteiro NG; Bim-Júnior O; Lisboa-Filho PN; Grandfield K; Okamoto R

Journal

Biomaterials Advances, Vol. 134, ,

Publisher

Elsevier

Publication Date

3 2022

DOI

10.1016/j.msec.2022.112688

ISSN

2772-9516