Journal article
High-Dose Thiamine Supplementation in Older Patients With Heart Failure: A Pilot Randomized Controlled Crossover Trial (THIAMINE-HF)
Abstract
Background: Thiamine supplementation may improve cardiac function in older adults with heart failure (HF). Our objectives were to determine the following: (i) the feasibility of conducting a large trial of thiamine supplementation in HF; and (ii) the effects of thiamine on clinical outcomes.
Methods: We conducted a double-blinded randomized placebo-controlled 2-period crossover feasibility study from June 2018 to April 2021. Adults aged ≥ 60 …
Authors
Wong EKC; Lee JY; Chow J; Power P; Jin L; Leong DP; Mbuagbaw L; Keen S; Yousuf H; Patterson C
Journal
CJC Open, Vol. 4, No. 6, pp. 532–539
Publisher
Elsevier
Publication Date
June 2022
DOI
10.1016/j.cjco.2022.02.007
ISSN
2589-790X