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Effectiveness of Tofacitinib for Hospitalized...
Journal article

Effectiveness of Tofacitinib for Hospitalized Patients with Acute Severe Ulcerative Colitis: Case Series

Abstract

BackgroundTreatment options for acute severe ulcerative colitis (ASUC) are limited. Tofacitinib, an approved treatment for moderate to severe ulcerative colitis, could be a potential rescue therapy for ASUC given its rapid onset of action.ObjectiveTo evaluate the effectiveness of tofacitinib in hospitalized patients with ASUC refractory to standard therapy in a real-world setting.MethodsRetrospective observational study of hospitalized adult …

Authors

Xiao Y; Benoit N; Sedano R; Jairath V; Narula N; McCurdy JD; Rosenfeld G; Afif W; Lakatos PL; Bessissow T

Journal

Digestive Diseases and Sciences, Vol. 67, No. 11, pp. 5213–5219

Publisher

Springer Nature

Publication Date

November 2022

DOI

10.1007/s10620-022-07439-2

ISSN

0163-2116