The burden of illness of severe nausea and vomiting of pregnancy in the United States Conferences uri icon

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  • OBJECTIVE: Our purpose was to determine the extent to which nausea and vomiting of pregnancy affects a woman's quality of life (QOL), ability to function, and health care resource use. STUDY DESIGN: We conducted an observational, multicenter, prospective cohort study by gathering data on the symptoms, QOL, and health care resource use from women who have nausea and vomiting of pregnancy. RESULTS: All 8 domains of health measured by the Short Form-36 QOL survey were limited by patient symptoms. This limitation manifested itself as patient-time loss from work and other normal activities, unpaid caregiver-time loss from work, and use of health care resources (eg, hospitalization). All types of time loss were correlated to severity of symptoms. CONCLUSIONS: Nausea and vomiting of pregnancy can severely reduce a woman's QOL and ability to function. The degree of limitation is associated with the severity of symptoms.


  • Attard, Cheryl L
  • Kohli, Michele A
  • Coleman, Suzanne
  • Bradley, Cathy
  • Hux, Margaret
  • Atanackovic, Gordana
  • Torrance, George Walter

publication date

  • May 2002