CFTR heterozygosity in severe airways disease with recurrent airway infections: a retrospective review

Rationale: Patients with asthma who have neutrophilic bronchitis may have an underlying cause leading to increased susceptibility to airway infections.

Methods: Retrospective review of patients with asthma who had a previous history of recurrent exacerbations that had been associated with airway or sinus infections referred to a tertiary asthma center between 2005-2020. Demographics, clinical features, and airway inflammation type determined by …