Variations in Takayasu arteritis characteristics in a cohort of patients with different racial backgrounds Academic Article uri icon

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abstract

  • Objectives

    We aimed to describe differences in disease characteristics and outcomes in Takayasu arteritis (TA) patients with different racial backgrounds.

    Methods

    This was a retrospective cohort study consisting of TA patients seen at specialty vasculitis clinics from five academic hospitals across Canada. Disease features, treatments and outcomes were compared between White and non-White patients.

    Results

    The cohort included 113 patients, of which 51 were White. Over 50% of the non-White patients were Asian. Compared to non-White patients, White patients had higher CRP and ESR at diagnosis (33.6 mg/l versus 9.4 mg/l, p = 0.033; and 51 mm/h versus 24 mm/h, p = 0.047; respectively), and were less likely to have baseline cardiovascular comorbidities including dyslipidemia (11.8% versus 29%, p = 0.037). There were no significant differences between racial groups for other disease characteristics or outcomes.

    Conclusion

    Patient race did not appear to play a significant role in determining disease characteristics and outcomes when comparing TA patients from various racial backgrounds living in the same country.

authors

  • Jiang, Zhuan
  • Lefebvre, Frédéric
  • Ross, Carolyn
  • Dehghan, Natasha
  • Fifi-Mah, Aurore
  • Khalidi, Nader
  • Pagnoux, Christian
  • Barra, Lillian

publication date

  • April 2022