Journal article
How to Use and Interpret the Results of a Platform Trial
Abstract
Platform trials are a type of randomized clinical trial that allow simultaneous comparison of multiple intervention groups against a single control group that serves as a common control based on a prespecified interim analysis plan. The platform trial design enables introduction of new interventions after the trial is initiated to evaluate multiple interventions in an ongoing manner using a single overarching protocol called a master (or core) …
Authors
Park JJH; Detry MA; Murthy S; Guyatt G; Mills EJ
Journal
JAMA, Vol. 327, No. 1, pp. 67–74
Publisher
American Medical Association (AMA)
Publication Date
January 4, 2022
DOI
10.1001/jama.2021.22507
ISSN
0098-7484