Journal article
Cannabinoid WIN55212‐2 impairs peanut‐allergic sensitization and promotes the generation of allergen‐specific regulatory T cells
Abstract
BACKGROUND: Cannabinoids are lipid-derived mediators with anti-inflammatory properties in different diseases. WIN55212-2, a non-selective synthetic cannabinoid, reduces immediate anaphylactic reactions in a mouse model of peanut allergy, but its capacity to prevent peanut-allergic sensitization and the underlying mechanisms remains largely unknown.
OBJECTIVE: To investigate the capacity of WIN55212-2 to immunomodulate peanut-stimulated human …
Authors
Angelina A; Jiménez‐Saiz R; Pérez‐Diego M; Maldonado A; Rückert B; Akdis M; Martín‐Fontecha M; Akdis CA; Palomares O
Journal
Clinical & Experimental Allergy, Vol. 52, No. 4, pp. 540–549
Publisher
Wiley
Publication Date
4 2022
DOI
10.1111/cea.14092
ISSN
0954-7894