Impact of mixed valvular disease on coarctation hemodynamics using patient-specific lumped parameter and Lattice Boltzmann modeling

The optimal course of intervention for patients with coexisting coarctation of the aorta (COA) and mixed valvular disease (combinations of aortic and mitral valve pathologies, MVD) is an area of contention and uncertainty. To effectively evaluate risk status and create guidelines for intervention aimed at minimizing the progression of cardiovascular disease, precise diagnostic information, which hinges on the quantification of aortic fluid …