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Decision Support Tool Identifies Ulcerative...
Journal article

Decision Support Tool Identifies Ulcerative Colitis Patients Most Likely to Achieve Remission With Vedolizumab vs Adalimumab

Abstract

BACKGROUND & AIMS: We have previously validated a clinical decision support tool (CDST) (vedolizumab CDST [VDZ-CDST]) for clinical and endoscopic remission with VDZ in ulcerative colitis (UC). We aim to expand the validation for predicting histoendoscopic mucosal improvement (HEMI) with VDZ vs adalimumab (ADA). METHODS: In a post hoc analysis of a clinical trial for VDZ vs ADA in moderate to severe UC (VARSITY trial; NCT02497469), comparative …

Authors

Dulai PS; Wong ECL; Reinisch W; Colombel J-F; Marshall JK; Narula N

Journal

Inflammatory Bowel Diseases, Vol. 28, No. 10, pp. 1555–1564

Publisher

Oxford University Press (OUP)

Publication Date

October 3, 2022

DOI

10.1093/ibd/izab310

ISSN

1078-0998