Journal article
Survival of human islets in microbeads containing high guluronic acid alginate crosslinked with Ca2+ and Ba2+
Abstract
BACKGROUND: The main hurdles to the widespread use of islet transplantation for the treatment of type 1 diabetes continue to be the insufficient number of appropriate donors and the need for immunosuppression. Microencapsulation has been proposed as a means to protect transplanted islets from the host's immune system.
METHODS: This study investigated the function of human pancreatic islets encapsulated in Ca(2+) /Ba(2+) -alginate microbeads …
Authors
Qi M; Mørch Y; Lacík I; Formo K; Marchese E; Wang Y; Danielson KK; Kinzer K; Wang S; Barbaro B
Journal
Xenotransplantation, Vol. 19, No. 6, pp. 355–364
Publisher
Wiley
Publication Date
November 2012
DOI
10.1111/xen.12009
ISSN
0908-665X