Journal article
The immunobiology of pig‐to‐nonhuman primate islet xenotransplantation: insights, innovation, and impact
Abstract
Previous studies of pig‐to‐non‐human primate (NHP) islet xenotransplantation have provided important insights into the immune recognition and effector pathways operative in this relevant preclinical model. The specifics of the xenograft product, microenvironment at the implantation site, and the immunosuppressive regimen significantly influence the mechanisms underlying the rejection of xenogeneic islets. Our current understanding of the …
Authors
Graham ML; Hennessy EA; Wang S; Martins KV; Suarez‐Pinzon WL; Bansal‐Pakala P; Flanagan BF; Murtaugh MP; Azimzadeh AM; Hancock WH
Journal
Xenotransplantation, Vol. 20, No. 1, pp. 50–50
Publisher
Wiley
Publication Date
January 2013
DOI
10.1111/xen.12014_8
ISSN
0908-665X