Kasabach-Merritt Syndrome With Partial Resection of Tumor, Reduction of Tumor Blood, and Vincristine Chemotherapy Journal Articles uri icon

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  • Kasabach-Merritt syndrome is a life-threatening and localized consumptive coagulopathy and characterized by profound thrombocytopenia and microangiopathic anemia. The huge tumor is the major cause of rapid platelet destruction, so we supposed that the reduction of tumor could reduce the platelet destruction and improve the clinical condition. In our cases, the vascular tumor occupied one of the extremities, head or face; however, removal of the whole tumor will result in the amputation of this extremity or the destruction of the face, and partial removal of the tumor and a U-shape suture to reduce tumor blood supply will be suitable. The wound could be repaired with skin graft or flaps. Vincristine chemotherapy after operation is necessary to prevent the enlargement of the remaining tumor.


  • Shen, Weiming
  • Cui, Jie
  • Chen, Jianbin
  • Zou, Jijun
  • Ji, Yi
  • Chen, Haini

publication date

  • January 2010