Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma

BACKGROUND: Asthma is a chronic condition in which sufferers may have occasional or frequent exacerbations resulting in visits to the emergency department (ED). Aminophylline has been used extensively to treat exacerbations in acute asthma settings; however, it's role is unclear especially with respect to any additional benefit when added to inhaled beta(2)-agonists. OBJECTIVES: To determine the magnitude of effect of the addition of …