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Bronchial thermoplasty guided by hyperpolarised...
Journal article

Bronchial thermoplasty guided by hyperpolarised gas magnetic resonance imaging in adults with severe asthma: a 1-year pilot randomised trial

Abstract

Patient-specific localisation of ventilation defects using hyperpolarised gas magnetic resonance imaging (MRI) introduces the possibility of regionally targeted bronchial thermoplasty (BT) for the treatment of severe asthma. We aimed to demonstrate that BT guided by MRI to ventilation defects reduces the number of radiofrequency activations while resulting in improved asthma quality-of-life and control scores that are non-inferior to standard …

Authors

Svenningsen S; Nair P; Eddy RL; McIntosh MJ; Kjarsgaard M; Lim HF; McCormack DG; Cox G; Parraga G

Journal

ERJ Open Research, Vol. 7, No. 3, pp. 00268–02021

Publisher

European Respiratory Society (ERS)

Publication Date

July 2021

DOI

10.1183/23120541.00268-2021

ISSN

2312-0541