Early Events in the Apoptotic Cascade Initiated in Cells Treated with Medium from the Progeny of Irradiated Cells

Genomic instability and the bystander effect have recently been linked experimentally. It has previously been shown that medium from irradiated cells can induce early events in the apoptotic cascade, such as mobilisation of intracellular calcium, loss of mitochondrial membrane potential and an increase in reactive oxygen species, in unhit cells. The aim of this study was to determine if medium from the progeny of irradiated cells could also …