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Efficacy and Safety of Therapeutic-Dose Heparin vs...
Journal article

Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19

Abstract

Importance: Hospitalized patients with COVID-19 are at risk for venous and arterial thromboembolism and death. Optimal thromboprophylaxis dosing in high-risk patients is unknown. Objective: To evaluate the effects of therapeutic-dose low-molecular-weight heparin (LMWH) vs institutional standard prophylactic or intermediate-dose heparins for thromboprophylaxis in high-risk hospitalized patients with COVID-19.

Authors

Spyropoulos AC; Goldin M; Giannis D; Diab W; Wang J; Khanijo S; Mignatti A; Gianos E; Cohen M; Sharifova G

Journal

JAMA Internal Medicine, Vol. 181, No. 12, pp. 1612–1620

Publisher

American Medical Association (AMA)

Publication Date

December 1, 2021

DOI

10.1001/jamainternmed.2021.6203

ISSN

2168-6106