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Draft Genome Sequence of Streptomyces silvensis...
Journal article

Draft Genome Sequence of Streptomyces silvensis ATCC 53525, a Producer of Novel Hormone Antagonists

Abstract

Streptomyces silvensis produces nonribosomal peptides that act as antagonists of the human oxytocin and vasopressin receptors. Here, we present the genome sequence of S. silvensis ATCC 53525 and demonstrate that this organism possesses a number of additional biosynthetic gene clusters and might be a promising source for genome-guided drug discovery efforts.

Authors

Johnston CW; Li Y; Magarvey NA

Journal

Microbiology Resource Announcements, Vol. 4, No. 1, pp. e00001–e00016

Publisher

American Society for Microbiology

Publication Date

February 25, 2016

DOI

10.1128/genomea.00001-16

ISSN

2169-8287