Journal article
Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity
Abstract
BACKGROUND & AIMS: Partially degraded gluten peptides from cereals trigger celiac disease (CD), an autoimmune enteropathy occurring in genetically susceptible persons. Susceptibility genes are necessary but not sufficient to induce CD, and additional environmental factors related to unfavorable alterations in the microbiota have been proposed. We investigated gluten metabolism by opportunistic pathogens and commensal duodenal bacteria and …
Authors
Caminero A; Galipeau HJ; McCarville JL; Johnston CW; Bernier SP; Russell AK; Jury J; Herran AR; Casqueiro J; Tye-Din JA
Journal
Gastroenterology, Vol. 151, No. 4, pp. 670–683
Publisher
Elsevier
Publication Date
October 2016
DOI
10.1053/j.gastro.2016.06.041
ISSN
0016-5085