Journal article
No Evidence for t(14;18)-Positive Cells in Newborns and Young Children until the Age of 10 Followed by a Linear Increase of the Prevalence in Healthy Individuals until the Age of 50 Years.
Abstract
Abstract
The t(14;18) translocation associated with follicular lymphoma can be detected in healthy individuals when highly sensitive PCR-based techniques are applied on blood and tissue samples. We studied the prevalence and frequency of t(14;18)-positive cells in a total of 632 healthy individuals (newborns to elderly adults). A standardized quantitative real-time PCR was carried out for the detection of t(14;18)-MBR-positive …
Authors
Schüler F; Dölken L; Dölken S; Hirt C; Fusch G; Bockholdt B; Lorenz G; Fusch C; Dolken G
Journal
Blood, Vol. 108, No. 11,
Publisher
American Society of Hematology
Publication Date
November 16, 2006
DOI
10.1182/blood.v108.11.4281.4281
ISSN
0006-4971