Journal article
Contribution of rare variant associations to neurodegenerative disease presentation
Abstract
Genetic factors contribute to neurodegenerative diseases, with high heritability estimates across diagnoses; however, a large portion of the genetic influence remains poorly understood. Many previous studies have attempted to fill the gaps by performing linkage analyses and association studies in individual disease cohorts, but have failed to consider the clinical and pathological overlap observed across neurodegenerative diseases and the …
Authors
Dilliott AA; Abdelhady A; Sunderland KM; Farhan SMK; Abrahao A; Binns MA; Black SE; Borrie M; Casaubon LK; Dowlatshahi D
Journal
npj Genomic Medicine, Vol. 6, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41525-021-00243-3
ISSN
2056-7944