Journal article
Evidence for local DNA influences on patterns of substitutions in the human -interferon gene family
Abstract
The evolutionary history of genes can be used to examine patterns of spontaneous mutation if the sequences are sufficiently extensive to provide reliable data. Many human alpha-interferon genes have been sequenced and they form a large multigene family including several pseudogenes. A phylogenetic history for 15 human interferon sequences was reconstructed and their ancestral sequences inferred using a maximum parsimony method. This …
Authors
Golding GB; Glickman BW
Journal
Genome, Vol. 28, No. 4, pp. 483–496
Publisher
Canadian Science Publishing
Publication Date
August 1, 1986
DOI
10.1139/g86-072
ISSN
0831-2796