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Examination of Prokaryotic Multipartite Genome...
Journal article

Examination of Prokaryotic Multipartite Genome Evolution through Experimental Genome Reduction

Abstract

Many bacteria carry two or more chromosome-like replicons. This occurs in pathogens such as Vibrio cholerea and Brucella abortis as well as in many N2-fixing plant symbionts including all isolates of the alfalfa root-nodule bacteria Sinorhizobium meliloti. Understanding the evolution and role of this multipartite genome organization will provide significant insight into these important organisms; yet this knowledge remains incomplete, in part, …

Authors

diCenzo GC; MacLean AM; Milunovic B; Golding GB; Finan TM

Journal

PLOS Genetics, Vol. 10, No. 10,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pgen.1004742

ISSN

1553-7390