Journal article
Effect of Chronic Treatment with D2 Allosteric Modulator PAOPA on the Expression of Cerebral Dopamine Neurotrophic Factor (CDNF) in Select Brain Regions
Abstract
Impairment in dopaminergic pathways has been implicated in several detrimental neuropsychiatric and neurodegenerative disorders, including schizophrenia and Parkinson’s disease. Current approved therapeutic drugs for such conditions treat the symptoms, not the underlying cause, as this requires long-term usage that often causes severe extrapyramidal side effects. A novel allosteric modulator, …
Authors
Tian Y; Daya R; Bhandari J; Joshi H; Thomson S; Patel V; Mishra R
Journal
International Journal of Peptide Research and Therapeutics, Vol. 27, No. 4, pp. 2551–2557
Publisher
Springer Nature
Publication Date
December 2021
DOI
10.1007/s10989-021-10272-2
ISSN
1573-3149