Journal article
A robust platform for chemical genomics in bacterial systems
Abstract
While genetic perturbation has been the conventional route to probing bacterial systems, small molecules are showing great promise as probes for cellular complexity. Indeed, systematic investigations of chemical-genetic interactions can provide new insights into cell networks and are often starting points for understanding the mechanism of action of novel chemical probes. We have developed a robust and sensitive platform for chemical-genomic …
Authors
French S; Mangat C; Bharat A; Côté J-P; Mori H; Brown ED
Journal
Molecular Biology of the Cell, Vol. 27, No. 6, pp. 1015–1025
Publisher
American Society for Cell Biology (ASCB)
Publication Date
March 15, 2016
DOI
10.1091/mbc.e15-08-0573
ISSN
1059-1524