Journal article
Apoptosis of Airway Epithelial Cells
Abstract
LL-37 is a human cationic host defense peptide that is present in the specific granules of neutrophils, produced by epithelial cells from a variety of tissues, and is upregulated during inflammation, infection, and injury. It has been proposed to have a variety of antimicrobial functions, including both direct antimicrobial activity and immunomodulatory functions. Using the TUNEL assay it was demonstrated that LL-37 induced apoptosis in vitro …
Authors
Lau YE; Bowdish DME; Cosseau C; Hancock REW; Davidson DJ
Journal
American Journal of Respiratory Cell and Molecular Biology, Vol. 34, No. 4, pp. 399–409
Publisher
American Thoracic Society
Publication Date
April 2006
DOI
10.1165/rcmb.2005-0170oc
ISSN
1044-1549