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Influence of depression on genetic predisposition...
Journal article

Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study

Abstract

We assessed the association between depression status and prevalent and incident type 2 diabetes (T2D) as well as the interaction between depression and a genetic risk score (GS) based on 20 T2D single-nucleotide polymorphisms (SNPs) in a multi-ethnic longitudinal study. We studied 17,375 participants at risk for dysglycemia. All participants had genotypic and phenotypic data collected at baseline and 9,930 participants were followed-up for a …

Authors

Garasia S; Samaan Z; Gerstein HC; Engert JC; Mohan V; Diaz R; Anand SS; Meyre D

Journal

Scientific Reports, Vol. 7, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41598-017-01406-y

ISSN

2045-2322