Integrated biological responses of zebrafish (Danio rerio) to analyze water quality in regions under anthropogenic influence Journal Articles uri icon

  • Overview
  • Research
  • Identity
  • Additional Document Info
  • View All


  • This study analyzed water quality in regions around Patos lagoon (Southern Brazil) that are under anthropogenic pressure. Water samples were collected from five different sites, including one used as a source for human consumption (COR) and others known to be influenced by human activities (IP). Danio rerio (Teleostei, Cyprinidae) organisms were exposed for 24h to these water samples, plus a control group. It was observed that: (1) reactive oxygen species levels were lower in COR and IP than in the control group; (2) glutamate-cysteine ligase (catalytic subunit) expression was higher in COR than in other sites; (3) exposure to all water samples affected long-term memory (LTM) when compared to control group. Thus, some water samples possess the ability to modulate the antioxidant system and to induce a decline in cognitive functions, as measured by LTM. The obtained results indicate that a combination of variables of different organization level (molecular, biochemical and behavioral) can be employed to analyze water quality in impacted regions.


  • Amado, LL
  • Rosa, CE
  • Castro, MR
  • Votto, AP
  • Santos, L Cougo
  • Marins, LFF
  • Trindade, GS
  • Fraga, DS
  • Damé, RCF
  • Barros, DM
  • Geracitano, LA
  • Bianchini, Adalto
  • de la Torre, FR
  • Monserrat, JM

publication date

  • March 2011