Allergen-derived T cell peptides in immunotherapy

The incidence of allergic diseases has continued to rise during the last 30 years. A combination of genetic and environmental factors is likely to be responsible for the increased prevalence of both allergic and autoimmune diseases. Whilst the majority of approaches towards treatment are palliative, specific allergen immunotherapy (SIT) is an approach that has been proven to be efficacious and disease-modifying. However, as a result of …