Variations in Neonatal Length of Stay of Babies Born Extremely Preterm: An International Comparison Between iNeo Networks Academic Article uri icon

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abstract

  • OBJECTIVE: To compare length of stay (LOS) in neonatal care for babies born extremely preterm admitted to networks participating in the International Network for Evaluating Outcomes of Neonates (iNeo). STUDY DESIGN: Data were extracted for babies admitted from 2014 to 2016 and born at 24 to 28 weeks of gestational age (n = 28 204). Median LOS was calculated for each network for babies who survived and those who died while in neonatal care. A linear regression model was used to investigate differences in LOS between networks after adjusting for gestational age, birth weight z score, sex, and multiplicity. A sensitivity analysis was conducted for babies who were discharged home directly. RESULTS: Observed median LOS for babies who survived was longest in Japan (107 days); this result persisted after adjustment (20.7 days more than reference, 95% CI 19.3-22.1). Finland had the shortest adjusted LOS (-4.8 days less than reference, 95% CI -7.3 to -2.3). For each week's increase in gestational age at birth, LOS decreased by 12.1 days (95% CI -12.3 to -11.9). Multiplicity and male sex predicted mean increases in LOS of 2.6 (95% CI 2.0-3.2) and 2.1 (95% CI 1.6-2.6) days, respectively. CONCLUSIONS: We identified between-network differences in LOS of up to 3 weeks for babies born extremely preterm. Some of these may be partly explained by differences in mortality, but unexplained variations also may be related to differences in clinical care practices and healthcare systems between countries.

authors

  • Seaton, Sarah E
  • Draper, Elizabeth S
  • Adams, Mark
  • Kusuda, Satoshi
  • Håkansson, Stellan
  • Helenius, Kjell
  • Reichman, Brian
  • Lehtonen, Liisa
  • Bassler, Dirk
  • Lee, Shoo K
  • Vento, Maximo
  • Darlow, Brian A
  • Rusconi, Franca
  • Beltempo, Marc
  • Isayama, Tetsuya
  • Lui, Kei
  • Norman, Mikael
  • Yang, Junmin
  • Shah, Prakesh S
  • Modi, Neena
  • Lui, Kei
  • Marshall, Peter
  • Schmidt, Peter
  • Dhawan, Anjali
  • Korostenski, Larissa
  • Travadi, Javeed Travadi
  • Sharp, Mary
  • Gill, Andy
  • Pillow, Jane
  • Stack, Jacqueline
  • Birch, Pita
  • Nothdurft, Karen
  • Cooke, Lucy
  • Casalaz, Dan
  • Holberton, Jim
  • Stewart, Alice
  • Downe, Lyn
  • Stewart, Michael
  • Berry, Andrew
  • Hunt, Rod
  • Morris, Peter
  • Paoli, Tony De
  • Lui, Kei
  • Bolisetty, Srinivas
  • Paradisis, Mary
  • Greenhalgh, Mark
  • Koorts, Pieter
  • Kuschel, Carl
  • Jacobs, Sue
  • Doyle, Lex
  • Craven, John
  • Numa, Andrew
  • Carlisle, Hazel
  • Badawi, Nadia
  • Popat, Himanshu
  • Koh, Guan
  • Davis, Jonathan
  • Luig, Melissa
  • Headley, Bevan
  • Andersen, Chad
  • Ng, Linda
  • Chambers, Georgina
  • Austin, Nicola
  • Lynn, Adrienne
  • Darlow, Brian
  • Edmonds, Liza
  • Mildenhall, Lindsay
  • Buksh, Mariam
  • Battin, Malcolm
  • Boom, Jutta van den
  • Richardson, Vaughan
  • Barker, David
  • Hammond, Barbara
  • Rajadurai, Victor Samuel
  • Lam, Simon
  • Fung, Genevieve
  • Shah, Prakesh S
  • Beltempo, Marc
  • Kanungo, Jaideep
  • Ting, Joseph
  • Cieslak, Zenon
  • Sherlock, Rebecca
  • Mehrem, Ayman Abou
  • Toye, Jennifer
  • Aziz, Khalid
  • Fajardo, Carlos
  • Bodani, Jaya
  • Strueby, Lannae
  • Seshia, Mary
  • Louis, Deepak
  • Alvaro, Ruben
  • Mukerji, Amit
  • Da Silva, Orlando
  • Adie, Mohammad
  • Lee, Kyong-Soon
  • Ng, Eugene
  • Lemyre, Brigitte
  • Daboval, Thierry
  • Khurshid, Faiza
  • Pelausa, Ermelinda
  • Barrington, Keith
  • Lapoint, Anie
  • Ethier, Guillaume
  • Drolet, Christine
  • Piedboeuf, Bruno
  • Claveau, Martine
  • St-Hilaire, Marie
  • Bertelle, Valerie
  • Masse, Edith
  • Canning, Roderick
  • Makary, Hala
  • Ojah, Cecil
  • Monterrosa, Luis
  • Emberley, Julie
  • Afifi, Jehier
  • Kajetanowicz, Andrzej
  • Lee, Shoo K
  • Metsäranta, Marjo
  • Lehtonen, Liisa
  • Tammela, Outi
  • Sankilampi, Ulla
  • Saarela, Timo
  • Morag, Iris
  • Zangen, Shmuel
  • Smolkin, Tatyana
  • Mimouni, Francis
  • Bader, David
  • Rothschild, Avi
  • Strauss, Zipora
  • Felszer, Clari
  • Omari, Hussam
  • Tov-Friedman, Smadar Even
  • Bar-Oz, Benjamin
  • Feldman, Michael
  • Saad, Nizar
  • Flidel-Rimon, Orna
  • Weisbrod, Meir
  • Lubin, Daniel
  • Litmanovitz, Ita
  • Kugelman, Amir
  • Shinwell, Eric
  • Klinger, Gil
  • Nijim, Yousif
  • Bin-Nun, Alona
  • Golan, Agneta
  • Mandel, Dror
  • Fleisher-Sheffer, Vered
  • Oron, Anat
  • Bakhrakh, Lev
  • Hattori, Satoshi
  • Shirai, Masaru
  • Ishioka, Toru
  • Mori, Toshihiko
  • Amizuka, Takasuke
  • Huchimukai, Toru
  • Yoshida, Hiroshi
  • Sasaki, Ayako
  • Shimizu, Junichi
  • Nakamura, Toshihiko
  • Maruyama, Mami
  • Matsumoto, Hiroshi
  • Hosokawa, Shinichi
  • Taki, Atsuko
  • Nakagawa, Machiko
  • Ko, Kyone
  • Uozumi, Azusa
  • Nakata, Setsuko
  • Shimazaki, Akira
  • Yoda, Tatsuya
  • Numata, Osamu
  • Imamura, Hiroaki
  • Kobayashi, Azusa
  • Tokuriki, Shuko
  • Uchida, Yasushi
  • Arai, Takahiro
  • Ito, Mitsuhiro
  • Ieda, Kuniko
  • Ono, Toshiyuki
  • Hayashi, Masashi
  • Maki, Kanemasa
  • Yamakawa, MieToru
  • Kawai, Masahiko
  • Fujii, Noriko
  • Shiomi, Kozue
  • Nozaki, Koji
  • Wada, Hiroshi
  • Kim, Taho
  • Tokunaga, Yasuyuki
  • Tokunaga, Yasuyuki
  • Takatera, Akihiro
  • Oshima, Toshio
  • Sumida, Hiroshi
  • Michinomae, Yae
  • Kusumoto, Yoshio
  • Yoshimoto, Seiji
  • Morisawa, Takeshi
  • Ohashi, Tamaki
  • Takahashi, Yukihiro
  • Sugimoto, Moriharu
  • Ono, Noriaki
  • Miyagawa, Shinichiro
  • Saijo, Takahiko
  • Yamagami, Takashi
  • Koyano, Kosuke
  • Kobayashi, Shoko
  • Kanda, Takeshi
  • Sakemi, Yoshihiro
  • Aoki, Mikio
  • Iida, Koichi
  • Goshi, Mitsushi
  • Maruyama, Yuko
  • Avila-Alvarez, Alejandro
  • Fernandez-Trisac, José Luis
  • Pico, Ma Luz Couce
  • Fernández Seara, María José
  • Gutiérrez, Andrés Martínez
  • Vizcaíno, Carolina
  • Iglesias, Miriam Salvador
  • Zaplana, Honorio Sánchez
  • Colomer, Belén Fernández
  • García López, José Enrique
  • Mozo, Rafael García
  • González Martínez, M Teresa
  • Sebastián, Ma Dolores Muro
  • Carbonell, Marta Balart
  • Barnusell, Joan Badia
  • Puiggròs, Mònica Domingo
  • Aloy, Josep Figueras
  • Mussons, Francesc Botet
  • Sanz, Israel Anquela
  • Galiana, Gemma Ginovart
  • Coroleu, W
  • Iriondo, Martin
  • Vilella, Laura Castells
  • Porta, Roser
  • Demestre, Xavier
  • Nadal, Silvia Martínez
  • de Frutos Martínez, Cristina
  • López Cuesta, María Jesús
  • Mora, Dolores Esquivel
  • Tardío, Joaquín Ortiz
  • Benavente, Isabel
  • Alonso, Almudena
  • Olmos, Ramón Aguilera
  • García Cabezas, Miguel A
  • Jiménez, Ma Dolores Martínez
  • Caballero, Ma Pilar Jaraba
  • Díaz, Ma Dolores Ordoñez
  • Fagundo, Alberto Trujillo
  • Canals, Lluis Mayol
  • García-Muñoz Rodrigo, Fermín
  • Martí, Lourdes Urquía
  • Moreno Galdo, María Fernanda
  • Suazo, José Antonio Hurtado
  • López, Eduardo Narbona
  • Fernández, José Uberos
  • Cortajarena Altuna, Miguel A
  • Zuriarrain, Oihana Muga
  • Navarro, David Mora
  • Domínguez, María Teresa
  • Ruiz del Prado, Ma Yolanda
  • Díez, Inés Esteban
  • Palau Benavides, María Teresa
  • Lapeña, Santiago
  • Prada, Teresa
  • Mir, Eduard Soler
  • Sánchez, Araceli Corredera
  • Vega, Enrique Criado
  • Prado, Náyade del
  • Fernández, Cristina
  • Vilaplana, Lucía Cabanillas
  • Pérez, Irene Cuadrado
  • Gómez, Luisa López
  • Comeche, Laura Domingo
  • Martín, Isabel Llana
  • Armengod, Carmen González
  • Labián, Carmen Muñoz
  • Muñoz, Ma José Santos
  • Bravo, Dorotea Blanco
  • Pérez, Vicente
  • Fernández, Ma Dolores Elorza
  • González, Celia Díaz
  • Segura, Susana Ares
  • Azorín, Manuela López
  • Jimenez, Ana Belén
  • Sánchez-Tamayo, Tomás
  • Moreno, Elías Tapia
  • González, María
  • Sánchez Martínez, José Enrique
  • Lloreda García, José María
  • Orayen, Concepción Goñi
  • González, Javier Vilas
  • Albo, María Suárez
  • Colmenero, Eva González
  • Gutiérrez González, Elena Pilar
  • Vacas del Arco, Beatriz
  • Fernández, Josefina Márquez
  • Gordillo, Laura Acosta
  • Asensio, Mercedes Granero
  • Díaz, Carmen Macías
  • Albújar, Mar
  • Jorge, Pedro Fuster
  • Romero, Sabina
  • Falero, Mónica Rivero
  • Escobar Izquierdo, Ana Belén
  • Capell, Javier Estañ
  • Macián, Ma Isabel Izquierdo
  • Vicente, Ma Mar Montejo
  • Caballero, Raquel Izquierdo
  • Martínez, Ma Mercedes
  • Euba, Aintzane
  • Serna, Amaya Rodríguez
  • López de Heredia Goya, Juan María
  • Legorburu, Alberto Pérez
  • Amorós, Ana Gutiérrez
  • Marugán Isabel, Víctor Manuel
  • González, Natalio Hernández
  • Gracia, Segundo Rite
  • Faci, Ma Purificación Ventura
  • Villagrasa, Ma Pilar Samper
  • Kofron, Jiri
  • Brodd, Katarina Strand
  • Odlind, Andreas
  • Alberg, Lars
  • Arwehed, Sofia
  • Hafström, Ola
  • Kasemo, Anna
  • Nederman, Karin
  • Åhman, Lars
  • Ingemarsson, Fredrik
  • Petersson, Henrik
  • Thurn, Pernilla
  • Albinsson, Eva
  • Selander, Bo
  • Abrahamsson, Thomas
  • Heimdahl, Ingela
  • Sveinsdottir, Kristbjorg
  • Wejryd, Erik
  • Hedlund, Anna
  • Söderberg, Maria Katarina
  • Navér, Lars
  • Brune, Thomas
  • Bäckström, Jens
  • Robinson, Johan
  • Farooqi, Aijaz
  • Normann, Erik
  • Fredriksson, Magnus
  • Palm, Anders
  • Rosenqvist, Urban
  • Walde, Bengt
  • Hagman, Cecilia
  • Ohlin, Andreas
  • Florell, Rein
  • Smedsaas-Löfvenberg, Agneta
  • Adams, Mark
  • Meyer, Philipp
  • Kusche, Rachel
  • Schulzke, Sven
  • Nelle, Mathias
  • Wagner, Bendicht
  • Riedel, Thomas
  • Kaczala, Grégoire
  • Pfister, Riccardo E
  • Tolsa, Jean-François
  • Roth, Matthias
  • Stocker, Martin
  • Laubscher, Bernhard
  • Malzacher, Andreas
  • Micallef, John P
  • Hegi, Lukas
  • Bassler, Dirk
  • Arlettaz, Romaine
  • Bernet, Vera
  • Dani, Carlo
  • Fiorini, Patrizio
  • Ghirri, Paolo
  • Tomasini, Barbara
  • Mittal, Anita
  • Kefas, Jonathan
  • Kamalanathan, Anand
  • Grosdenier, Michael
  • Dewhurst, Christopher
  • Bontea, Andreea
  • Webb, Delyth
  • Garr, Ross
  • Hassan, Ahmed
  • Ambadkar, Priyadarshan
  • Dyke, Mark
  • McDevitt, Katharine
  • Rewitzky, Glynis
  • D'Amore, Angela
  • Kamath, P
  • Settle, Paul
  • Maddock, Natasha
  • Edi-Osagie, Ngozi
  • Zipitis, Christos
  • Heal, Carrie
  • Birch, Jacqeline
  • Hasib, Abdul
  • Soe, Aung
  • Abdul-Malik, Bushra
  • Kisat, Hamudi
  • Vasu, Vimal
  • Sivashankar, Savi
  • Gupta, Richa
  • Rawlingson, Chris
  • Wickham, Tim
  • Theron, Marice
  • Kendall, Giles
  • Gupta, Aashish
  • Aladangady, Narendra
  • Ali, Imdad
  • Jain, Neeraj
  • Mannan, Khalid
  • Murthy, Vadivelam
  • Sullivan, Caroline
  • Chuang, Shu-Ling
  • Bate, Tristan
  • Tyszcuzk, Lidia
  • Tyszcuzk, Lidia
  • Lee, Geraint
  • Obi, Ozioma
  • Chang, John
  • Pai, Vinay
  • Huddy, Charlotte
  • Yasin, Salim
  • Nicholl, Richard
  • Pandey, Poornima
  • Cusack, Jonathan
  • Kairamkonda, Venkatesh
  • Muogbo, Dominic
  • Harry, Liza
  • Surana, Pinki
  • Broggio, Penny
  • Surana, Pinki
  • Harry, Liza
  • Pillay, Tilly
  • Deshpande, Sanjeev
  • Mahadevan
  • Moore, Alison
  • Bastani, Porus
  • Garbash, Mehdi
  • Lal, Mithilesh
  • Abu-Harb, Majd
  • Garbash, Mehdi
  • Allwood, Alex
  • Selter, Michael
  • Munyard, Paul
  • Bartle, David
  • Paul, Siba
  • Whincup, Graham
  • Rekha, Sanghavi
  • Amess, Philip
  • Obi, Ben
  • Amess, Philip
  • Reynolds, Peter
  • Misra, Indranil
  • De Halpert, Peter
  • Salgia, Sanjay
  • Sanghavi, Rekha
  • Paul, Nicola
  • Deketelaere, Abby
  • Khashu, Minesh
  • Johnson, Mark
  • Groves, Charlotte
  • Baird, Jim
  • Brennan, Nick
  • Vamvakiti, Katia
  • McIntyre, John
  • Holman, Jennifer
  • Jones, Stephen
  • Pike, Alison
  • Cairns, Pamela
  • Eaton, Megan
  • Schwarz, Karin
  • Gibson, David
  • Miall, Lawrence
  • Gibson, David
  • Krishnamurthy, Dr
  • Narayanan, Sankara

publication date

  • June 2021