Validation and Evaluation of Model-Based Cross-Talk Compensation Method in Simultaneous $^{99{\rm m}}{\rm Tc}$ Stress and $^{{\rm 201}}{\rm T}1$ Rest Myocardial Perfusion SPECT

Simultaneous acquisition of $^{99{\rm m}}{\rm Tc}$ stress and $^{{\rm 201}}{\rm T}1$ rest myocardial perfusion SPECT has several potential advantages, but the image quality is degraded by cross-talk between the Tc and T1 data. We have previously developed down-scatter and Pb x-ray models for cross-talk compensation. In this work, we validated these models by comparing the crosstalk from $^{99{\rm m}}{\rm Tc}$ to the T1 window calculated using …