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The influence of antenatal exposure to phthalates...
Journal article

The influence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study

Abstract

We hypothesised that antenatal exposure to ubiquitous phthalates may lead to an earlier menarche and a lower prevalence of polycystic ovarian syndrome (PCOS) and polycystic ovarian morphology (PCO) in adolescence. The Western Australian Pregnancy Cohort (Raine) Study recruited 3000 women at 18 weeks of gestation in 1989-1991, 1377 had antenatal serum stored without thawing at -80 °C. An unselected subset was evaluated in the early follicular …

Authors

Hart R; Doherty DA; Frederiksen H; Keelan JA; Hickey M; Sloboda D; Pennell CE; Newnham JP; Skakkebaek NE; Main KM

Journal

Reproduction, Vol. 147, No. 4, pp. 379–390

Publisher

Bioscientifica

Publication Date

2014

DOI

10.1530/rep-13-0331

ISSN

1470-1626