Hematopoiesis from Human Embryonic Stem Cells Journal Articles

abstract

• Abstract:  Human embryonic stem cells (hESCs) have the capacity to differentiate into multiple lineages, such as neural and hepatic, and include the ability to form hematopoietic cells. Efforts to develop efficient methods to induce hematopoietic differentiation effectively from hESCs, and generate primitive blood stem cells with multilineage hematopoietic repopulating function, are ongoing in several laboratories. Here, we will discuss the past and current progress of our laboratory in this area, and share our ideas to further this use of hESCs in both experimental and clinical hematology.

authors

• Bhatia, Mick

status

• published 

publication date

• June 2007

has subject area

• Cell Differentiation (MeSH)
• Cell Line (MeSH)
• Cell Lineage (MeSH)
• Cell Proliferation (MeSH)
• Embryo, Mammalian (MeSH)
• Embryonic Stem Cells (MeSH)
• Gene Expression Regulation (MeSH)
• General Science & Technology (Science Metrix)
• Hematology (MeSH)
• Hematopoiesis (MeSH)
• Hematopoietic Stem Cells (MeSH)
• Humans (MeSH)
• Models, Biological (MeSH)
• Stem Cells (MeSH)

published in

• Annals of the New York Academy of Sciences  Journal

keywords

• Cell Differentiation
• Cell Line
• Cell Lineage
• Cell Proliferation
• Embryo, Mammalian
• Embryonic Stem Cells
• Gene Expression Regulation
• Hematology
• Hematopoiesis
• Hematopoietic Stem Cells
• Humans
• Models, Biological
• Stem Cells

Digital Object Identifier (DOI)

• 10.1196/annals.1392.007

PubMed ID

• 17332088

start page

• 219

end page

• 222

volume

• 1106

issue

• 1