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Comprehensive microRNA expression profiling of the...
Journal article

Comprehensive microRNA expression profiling of the hematopoietic hierarchy

Abstract

The hematopoietic system produces a large number of highly specialized cell types that are derived through a hierarchical differentiation process from a common stem cell population. miRNAs are critical players in orchestrating this differentiation. Here, we report the development and application of a high-throughput microfluidic real-time quantitative PCR (RT-qPCR) approach for generating global miRNA profiles for 27 phenotypically distinct …

Authors

Petriv OI; Kuchenbauer F; Delaney AD; Lecault V; White A; Kent D; Marmolejo L; Heuser M; Berg T; Copley M

Journal

Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, No. 35, pp. 15443–15448

Publisher

Proceedings of the National Academy of Sciences

Publication Date

August 31, 2010

DOI

10.1073/pnas.1009320107

ISSN

0027-8424