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Bone marrow localization and functional properties...
Journal article

Bone marrow localization and functional properties of human hematopoietic stem cells

Abstract

PURPOSE OF REVIEW: Historically, studies of the hematopoietic stem cell (HSC) microenvironment in bone marrow have focused on the identification of individual supportive cell lineages likely to be responsible for maintaining HSCs in a self-renewing and regenerative state. More recently, awareness has developed regarding the broad and dynamic heterogeneity of nonhematopoietic cells that reside within the bone marrow space. We review recent …

Authors

Boyd AL; Bhatia M

Journal

Current Opinion in Hematology, Vol. 21, No. 4, pp. 249–255

Publisher

Wolters Kluwer

Publication Date

July 2014

DOI

10.1097/moh.0000000000000055

ISSN

1065-6251