Back Cover: In Vitro Selection of a DNA Aptamer Targeting Degraded Protein Fragments for Biosensing (Angew. Chem. Int. Ed. 20/2020)

A DNA aptamer targeting naturally degraded protein fragments was selected by M. Liu, J. D. Brennan, Y. Li, and co‐workers in their Communication on page 7706. The aptamer binds a degraded form of toxin B from Clostridium difficile and can detect this protein fragment in human stool. This method offers a way to discover DNA aptamers that cannot be selected using purified proteins, thus expanding the practical utility of DNA aptamers in clinical diagnosis.