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Increased Mitochondrial Mass in Cells with...
Journal article

Increased Mitochondrial Mass in Cells with Functionally Compromised Mitochondria after Exposure to both Direct Radiation and Bystander Factors

Abstract

The bystander effect describes radiation-like damage in unirradiated cells either in the vicinity of irradiated cells or exposed to medium from irradiated cells. This study aimed to further characterize the poorly understood mitochondrial response to both direct irradiation and bystander factor(s) in human keratinocytes (HPV-G) and Chinese hamster ovarian cells (CHO-K1). Oxygen consumption rates were determined during periods of state 4, state …

Authors

Nugent SME; Mothersill CE; Seymour C; McClean B; Lyng FM; Murphy JEJ

Journal

Radiation Research, Vol. 168, No. 1, pp. 134–142

Publisher

Radiation Research Society

Publication Date

July 2007

DOI

10.1667/rr0769.1

ISSN

0033-7587