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Temporal Dynamics and Evolution of SARS-CoV-2...
Journal article

Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada

Abstract

Genome-wide variation in SARS-CoV-2 reveals evolution and transmission dynamics which are critical considerations for disease control and prevention decisions. Here, we review estimates of the genome-wide viral mutation rates, summarize current COVID-19 case load in the province of Ontario, Canada (5 January 2021), and analyze published SARS-CoV-2 genomes from Ontario (collected prior to 24 November 2020) to test for more infectious genetic …

Authors

Sjaarda CP; Guthrie JL; Mubareka S; Simpson JT; Hamelin B; Wong H; Mortimer L; Slinger R; McArthur AG; Desjardins M

Journal

mSphere, Vol. 6, No. 3, pp. 10.1128/msphere.00011–10.1128/msphere.00021

Publisher

American Society for Microbiology

Publication Date

June 30, 2021

DOI

10.1128/msphere.00011-21

ISSN

1556-6811