Journal article
Exosomes are released by bystander cells exposed to radiation-induced biophoton signals: Reconciling the mechanisms mediating the bystander effect
Abstract
OBJECTIVE: The objective of our study was to explore a possible molecular mechanism by which ultraviolet (UV) biophotons could elicit bystander responses in reporter cells and resolve the problem of seemingly mutually exclusive mechanisms of a physical UV signal & a soluble factor-mediated bystander signal.
METHODS: The human colon carcinoma cell line, HCT116 p53 +/+, was directly irradiated with 0.5 Gy tritium beta particles to induce …
Authors
Le M; Fernandez-Palomo C; McNeill FE; Seymour CB; Rainbow AJ; Mothersill CE
Journal
PLOS ONE, Vol. 12, No. 3,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0173685
ISSN
1932-6203