Journal article
MAUI (MBI Analysis User Interface)—An image processing pipeline for Multiplexed Mass Based Imaging
Abstract
Mass Based Imaging (MBI) technologies such as Multiplexed Ion Beam Imaging by time of flight (MIBI-TOF) and Imaging Mass Cytometry (IMC) allow for the simultaneous measurement of the expression levels of 40 or more proteins in biological tissue, providing insight into cellular phenotypes and organization in situ. Imaging artifacts, resulting from the sample, assay or instrumentation complicate downstream analyses and require correction by …
Authors
Baranski A; Milo I; Greenbaum S; Oliveria J-P; Mrdjen D; Angelo M; Keren L
Journal
PLOS Computational Biology, Vol. 17, No. 4,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pcbi.1008887
ISSN
1553-734X