TERMINAL TRANSFERASE IN HUMAN BONE-MARROW LYMPHOCYTES Academic Article uri icon

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abstract

  • Activity of the enzyme terminal transferase (TdT) has been localised in normal human bone-marrow lymphocytes. These cells may represent a prothymocyte population, which, on malignant transformation, may give rise to acute lymphoblastic leukaemia, and to some cases of chronic granulocytic leukaemia in the blastic phase.

publication date

  • March 1976