TERMINAL TRANSFERASE IN HUMAN BONE-MARROW...

TERMINAL TRANSFERASE IN HUMAN BONE-MARROW LYMPHOCYTES

Abstract

Activity of the enzyme terminal transferase (TdT) has been localised in normal human bone-marrow lymphocytes. These cells may represent a prothymocyte population, which, on malignant transformation, may give rise to acute lymphoblastic leukaemia, and to some cases of chronic granulocytic leukaemia in the blastic phase.

Authors

Barr R; Sarin P; Perry S

Journal

The Lancet, Vol. 307, No. 7958, pp. 508–509

Publisher

Elsevier

Publication Date

March 6, 1976

DOI

10.1016/s0140-6736(76)90295-6

ISSN

0140-6736

Associated Experts

Ronald Duncan Barr

Professor Emeritus, Faculty of Health Sciences

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