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Comparative efficacy, tolerability and safety of...
Journal article

Comparative efficacy, tolerability and safety of dolutegravir and efavirenz 400mg among antiretroviral therapies for first-line HIV treatment: A systematic literature review and network meta-analysis

Abstract

BACKGROUND: To inform World Health Organization (WHO) global guidelines, we updated and expanded the evidence base to assess the comparative efficacy, tolerability, and safety of first-line antiretroviral therapy (ART) regimens. METHODS: We searched Embase, Medline and CENTRAL on 28 February 2020 to update the systematic literature review of clinical trials comparing recommended first-line ART that informed previous WHO guidelines. Outcomes …

Authors

Kanters S; Vitoria M; Zoratti M; Doherty M; Penazzato M; Rangaraj A; Ford N; Thorlund K; Anis AH; Karim ME

Journal

EClinicalMedicine, Vol. 28, ,

Publisher

Elsevier

Publication Date

November 2020

DOI

10.1016/j.eclinm.2020.100573

ISSN

2589-5370