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Sex differences in neuro(auto)immunity and chronic...
Journal article

Sex differences in neuro(auto)immunity and chronic sciatic nerve pain

Abstract

Chronic pain occurs with greater frequency in women, with a parallel sexually dimorphic trend reported in sufferers of many autoimmune diseases. There is a need to continue examining neuro-immune-endocrine crosstalk in the context of sexual dimorphisms in chronic pain. Several phenomena in particular need to be further explored. In patients, autoantibodies to neural antigens have been associated with sensory pathway hyper-excitability, and the …

Authors

Linher-Melville K; Shah A; Singh G

Journal

Biology of Sex Differences, Vol. 11, No. 1,

Publisher

Springer Nature

Publication Date

December 2020

DOI

10.1186/s13293-020-00339-y

ISSN

2042-6410