Journal article
Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects
Abstract
BackgroundClearly structured and comprehensive protocols are an essential component to ensure safety of participants, data validity, successful conduct, and credibility of results of randomized clinical trials (RCTs). Funding agencies, research ethics committees (RECs), regulatory agencies, medical journals, systematic reviewers, and other stakeholders rely on protocols to appraise the conduct and reporting of RCTs. In response to evidence of …
Authors
Gryaznov D; Odutayo A; von Niederhäusern B; Speich B; Kasenda B; Ojeda-Ruiz E; Blümle A; Schandelmaier S; Mertz D; Tomonaga Y
Journal
Trials, Vol. 21, No. 1,
Publisher
Springer Nature
Publication Date
December 2020
DOI
10.1186/s13063-020-04808-y
ISSN
1468-6708