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Rapid Screening of Urinary 1‑Hydroxypyrene...
Journal article

Rapid Screening of Urinary 1‑Hydroxypyrene Glucuronide by Multisegment Injection–Capillary Electrophoresis–Tandem Mass Spectrometry: A High-Throughput Method for Biomonitoring of Recent Smoke Exposures

Abstract

Urinary 1-hydroxypyrene (HP) is a widely used biomarker of polycyclic aromatic hydrocarbon exposure relevant for biomonitoring the deleterious health impacts from tobacco smoke and ambient air pollution, as well as the hazards of certain occupations. Conventional methods for urinary HP analysis based on liquid chromatography with native fluorescence detection or tandem mass spectrometry (MS/MS) and gas chromatography-mass spectrometry (GC-MS) …

Authors

Gill B; Jobst K; Britz-McKibbin P

Journal

Analytical Chemistry, Vol. 92, No. 19, pp. 13558–13564

Publisher

American Chemical Society (ACS)

Publication Date

October 6, 2020

DOI

10.1021/acs.analchem.0c03212

ISSN

0003-2700