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Efficacy and Safety of nab-Paclitaxel vs...
Journal article

Efficacy and Safety of nab-Paclitaxel vs Paclitaxel on Survival in Patients With Platinum-Refractory Metastatic Urothelial Cancer

Abstract

IMPORTANCE: Treatment options for platinum-refractory metastatic urothelial cancer (mUC) are limited, and outcomes remain poor. Nab-paclitaxel is an albumin-bound formulation of paclitaxel showing promising activity and tolerability in a prior single-arm trial. OBJECTIVES: To evaluate the efficacy and safety of nab-paclitaxel vs paclitaxel in platinum-refractory mUC.

Authors

Sridhar SS; Blais N; Tran B; Reaume MN; North SA; Stockler MR; N. K; Fleshner NE; Liu G; Robinson JW

Journal

JAMA Oncology, Vol. 6, No. 11, pp. 1751–1758

Publisher

American Medical Association (AMA)

Publication Date

November 1, 2020

DOI

10.1001/jamaoncol.2020.3927

ISSN

2374-2437