Journal article
Power Analysis for Population-Based Longitudinal Studies Investigating Gene-Environment Interactions in Chronic Diseases: A Simulation Study
Abstract
Conventional methods for sample size calculation for population-based longitudinal studies tend to overestimate the statistical power by overlooking important determinants of the required sample size, such as the measurement errors and unmeasured etiological determinants, etc. In contrast, a simulation-based sample size calculation, if designed properly, allows these determinants to be taken into account and offers flexibility in accommodating …
Authors
Ma J; Thabane L; Beyene J; Raina P
Journal
PLOS ONE, Vol. 11, No. 2,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0149940
ISSN
1932-6203