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The role of fecal calprotectin in the diagnosis of...
Journal article

The role of fecal calprotectin in the diagnosis of acute pouchitis following IPAA for ulcerative colitis: a systematic clinical review

Abstract

PurposeTotal proctocolectomy (TPC) with ileal pouch anal anastomosis (IPAA) is commonly performed for patients with refractory ulcerative colitis (UC). Pouchitis occurs in 20–50% of these patients. Fecal calprotectin is a biomarker that correlates well with the pouchitis disease activity index. However, its role in the diagnosis and management of acute pouchitis has not been thoroughly defined. The aim of this study is to review previously …

Authors

McKechnie T; Lee Y; Kruse C; Ramji K; Springer JE; Wood T; Doumouras AG; Hong D; Eskicioglu C

Journal

International Journal of Colorectal Disease, Vol. 35, No. 9, pp. 1619–1628

Publisher

Springer Nature

Publication Date

September 2020

DOI

10.1007/s00384-020-03669-w

ISSN

0179-1958